GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs2275426 | 1 | rs12405451 | chr1:46384326 | CCDC163P | chr1:45960581-45965646:- | -0.35 | -6.56 | 1.75E-10 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs12409773 | chr1:46358831 | CCDC163P | chr1:45960581-45965646:- | -0.38 | -7.18 | 3.73E-12 | Body mass index |
| BLCA | cis | rs3931020 | 1 | rs12410060 | chr1:75245848 | CRYZ | chr1:75171175-75199092:- | -0.27 | -4.14 | 4.28E-5 | Resistin levels |
| BLCA | cis | rs2275426 | 1 | rs12410071 | chr1:46358886 | CCDC163P | chr1:45960581-45965646:- | -0.38 | -7.15 | 4.53E-12 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs12411269 | chr1:46271052 | CCDC163P | chr1:45960581-45965646:- | -0.37 | -6.99 | 1.19E-11 | Body mass index |
| BLCA | cis | rs9527 | 1 | rs12416687 | chr10:104629011 | C10orf32 | chr10:104613967-104624718:+ | -0.37 | -5.7 | 2.39E-8 | Arsenic metabolism |
| BLCA | cis | rs7927771 | 1 | rs12418852 | chr11:47868853 | C1QTNF4 | chr11:47611216-47615961:- | -0.3 | -5.55 | 5.34E-8 | Subjective well-being |
| BLCA | cis | rs7927771 | 1 | rs12419692 | chr11:47624714 | C1QTNF4 | chr11:47611216-47615961:- | 0.29 | 5.73 | 2.0E-8 | Subjective well-being |
| BLCA | cis | rs7927771 | 1 | rs12421210 | chr11:47779586 | C1QTNF4 | chr11:47611216-47615961:- | -0.3 | -5.57 | 4.7E-8 | Subjective well-being |
| BLCA | cis | rs12422267 | 1 | rs12422267 | chr12:132601596 | DDX51 | chr12:132621142-132628880:- | 0.49 | 4.4 | 1.38E-5 | Plasma amyloid beta peptide concentrations (ABx-40) |
| BLCA | cis | rs12422267 | 1 | rs12422267 | chr12:132601596 | EP400NL | chr12:132568828-132600084:+;chr12 | -0.61 | -5.21 | 3.05E-7 | Plasma amyloid beta peptide concentrations (ABx-40) |
| BLCA | cis | rs7112513 | 1 | rs1242229 | chr11:117062370 | PCSK7 | chr11:117075789-117102811:- | -0.37 | -4.7 | 3.57E-6 | Protein quantitative trait loci |
| BLCA | cis | rs2404602 | 1 | rs12441433 | chr15:76816015 | SCAPER | chr15:76640529-77197744:- | -0.22 | -4.75 | 2.86E-6 | Blood metabolite levels |
| BLCA | cis | rs2251844 | 1 | rs12443102 | chr15:43932103 | ADAL | chr15:43622872-43646094:+ | -0.39 | -4.42 | 1.26E-5 | Tumor biomarkers |
| BLCA | cis | rs2251844 | 1 | rs12443102 | chr15:43932103 | CATSPER2 | chr15:43922774-43959900:- | -0.33 | -4.78 | 2.56E-6 | Tumor biomarkers |